William Pinckney Cain (August 3, 1843-October 2, 1895) built the house in St. Matthews about 1872 with unusual architecture. Cain married Adella Clark, who taught pupils at home. All the Cain children were born in the house. George Wannamaker, who died in 1921, also lived in the house with his wife Lillie Bates Wannamaker.